Induction of functional xeno-free MSCs from human iPSCs via a neural crest cell lineage

Abstract Mesenchymal stem/stromal cells (MSCs) are adult multipotent stem cells. Here, we induced MSCs from human induced pluripotent stem cells (iPSCs) via a neural crest cell (NCC) lineage under xeno-free conditions and evaluated their in vivo functions. We modified a previous MSC induction method...

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Bibliographic Details
Main Authors: Daisuke Kamiya, Nana Takenaka-Ninagawa, Souta Motoike, Mikihito Kajiya, Teppei Akaboshi, Chengzhu Zhao, Mitsuaki Shibata, Sho Senda, Yayoi Toyooka, Hidetoshi Sakurai, Hidemi Kurihara, Makoto Ikeya
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-022-00241-8