Improved in Vivo Whole-Animal Detection Limits of Green Fluorescent Protein–Expressing Tumor Lines by Spectral Fluorescence Imaging

Green fluorescent protein (GFP) has been used for cell tracking and imaging gene expression in superficial or surgically exposed structures. However, in vivo murine imaging is often limited by several factors, including scatter and attenuation with depth and overlapping autofluorescence. The autoflu...

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Bibliographic Details
Main Authors: Jenny M. Tam, Rabi Upadhyay, Mikael J. Pittet, Ralph Weissleder, Umar Mahmood
Format: Article
Language:English
Published: SAGE Publishing 2007-07-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2007.00023