Single-Cell Transcriptomics Reveals Conserved Regulatory Networks in Human and Mouse Interneuron Development

Inhibitory GABAergic interneurons originate in the embryonic medial ganglionic eminence (MGE) and control network activity in the neocortex. Dysfunction of these cells is believed to lead to runaway excitation underlying seizure-based neurological disorders such as epilepsy, autism, and schizophreni...

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Bibliographic Details
Main Authors: Francesca Keefe, Jimena Monzón-Sandoval, Anne E. Rosser, Caleb Webber, Meng Li
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/9/8122