Case Report: Identification of Multiple TERT and FGFR2 Gene Fusions in a Pineal Region Glioblastoma Case

Case Report: Identification of Multiple TERT and FGFR2 Gene Fusions in a Pineal Region Glioblastoma Case

As an oncogenic somatic variant, telomerase reverse transcriptase promoter (TERTp) mutations are frequently observed in adult glioblastoma (GBM). Alternatively, we report the first case of glioblastoma with TERT amplification accompanied by multiple TERT and FGFR2 gene fusions instead of TERTp mutat...

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Bibliographic Details
Main Authors: Xing Guo, Teng Chen, Shiming Chen, Chao Song, Dezhi Shan, Shujun Xu, Shuo Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
somatic variation
TERT
FGFR2
amplification
gene fusion
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.739309/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.739309/full

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