Nicorandil directly and cyclic GMP-dependently opens K+ channels in human bypass grafts

Nicorandil directly and cyclic GMP-dependently opens K+ channels in human bypass grafts

As we previously demonstrated the role of different K+ channels in the action of nicorandil on human saphenous vein (HSV) and human internal mammary artery (HIMA), this study aimed to analyse the contribution of the cGMP pathway in nicorandil-induced vasorelaxation and to determine the involvement o...

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Bibliographic Details
Main Authors: Marija Marinko, Aleksandra Novakovic, Dragoslav Nenezic, Ivan Stojanovic, Predrag Milojevic, Miomir Jovic, Nenad Ugresic, Vladimir Kanjuh, Qin Yang, Guo-Wei He
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Journal of Pharmacological Sciences
Subjects:
Nicorandil
Cyclic GMP
K channel
Vasorelaxation
Human bypass grafts
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861315000596

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http://www.sciencedirect.com/science/article/pii/S1347861315000596

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