Sildenafil improves hemodynamic changes caused by acute pulmonary embolism by inhibiting Rho kinase activity
Objective This study examined the effects of sildenafil on acute pulmonary embolism (APE) using a rat model. Methods Sprague–Dawley rats were randomly divided into the sham, pulmonary thromboembolism (PTE), and sildenafil groups. The sham and PTE groups received normal saline once daily via gavage f...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2024-04-01
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Series: | Journal of International Medical Research |
Online Access: | https://doi.org/10.1177/03000605241240938 |