The effects of midazolam and sevoflurane on the GABA receptors with alternatively spliced variants of the γ2 subunit

The effects of midazolam and sevoflurane on the GABA receptors with alternatively spliced variants of the γ2 subunit

BackgroundEmergence agitation after sevoflurane anesthesia in children can be prevented by midazolam. Alternative splicing of the GABAA receptor changes with age. Therefore, we hypothesized that alternative splicing of the γ2 subunit affects the GABA current when applying sevoflurane and midazolam.M...

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Bibliographic Details
Main Authors: Woosik Eom, Jung Min Lee, Jeongmi Park, Kyungho Choi, Sung-Jun Jung, Hee-Soo Kim
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2011-02-01
Series:Korean Journal of Anesthesiology
Subjects:
agitation
alternative splicing
gaba receptor
gamma 2 subunit
midazolam
sevoflurane
Online Access:http://ekja.org/upload/pdf/kjae-60-109.pdf

Internet

http://ekja.org/upload/pdf/kjae-60-109.pdf

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