CGHnormaliter: an iterative strategy to enhance normalization of array CGH data with imbalanced aberrations

<p>Abstract</p> <p>Background</p> <p>Array comparative genomic hybridization (aCGH) is a popular technique for detection of genomic copy number imbalances. These play a critical role in the onset of various types of cancer. In the analysis of aCGH data, normalization is...

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Bibliographic Details
Main Authors: Pirovano Walter, Hettling Hannes, Binsl Thomas W, van Houte Bart PP, Heringa Jaap
Format: Article
Language:English
Published: BMC 2009-08-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/10/401