Detection of pathogens from resected heart valves of patients with infective endocarditis by next-generation sequencing

Objectives: Identification of the underlying pathogens of infective endocarditis (IE) is critical for precision therapy. Methods: We evaluated a metagenomic method with next-generation sequencing (NGS) for the direct detection of pathogens from the resected valves of 44 IE patients and seven rejecte...

Full description

Bibliographic Details
Main Authors: Jun Cheng, Huan Hu, Wei Fang, Duozhi Shi, Chen Liang, Yang Sun, GuoFeng Gao, Hao Wang, Qian Zhang, LiQing Wang, HongLong Wu, Long Hu, Luyao Chen, Jin Zhang, Shela Lee, FeiYan Wang, Zhou Zhou
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971219301341