KRAS mutant lung cancer: progress thus far on an elusive therapeutic target

AbstractThe KRAS mutation remains the most common driver mutation in patients with non‐small cell lung cancer (NSCLC) and confers a poor prognosis. Thus far, efforts to target this mutation over the last two decades have been unsuccessful. Over the past 5 years, many efforts to develop drugs that ta...

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Bibliographic Details
Main Authors: Saveri Bhattacharya, Mark A. Socinski, Timothy F. Burns
Format: Article
Language:English
Published: Wiley 2015-12-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s40169-015-0075-0