An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption

An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption

Fat is delivered to tissues by apoB-containing lipoproteins synthesized in the liver and intestine with the help of an intracellular chaperone, microsomal triglyceride transfer protein (MTP). Leptin, a hormone secreted by adipose tissue, acts in the brain and on peripheral tissues to regulate fat st...

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Bibliographic Details
Main Authors: Jahangir Iqbal, Xiaosong Li, Benny Hung-Junn Chang, Lawrence Chan, Gary J. Schwartz, Streamson C. Chua, Jr., M. Mahmood Hussain
Format: Article
Language:English
Published: Elsevier 2010-07-01
Series:Journal of Lipid Research
Subjects:
MTP
apoB
fat absorption
leptin receptor
POMC
AGRP
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520371157

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http://www.sciencedirect.com/science/article/pii/S0022227520371157

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