Ribosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX network.
Changes to the nucleolus, the site of ribosome production, have long been linked to cancer, and mutations in several ribosomal proteins (RPs) have been associated with an increased risk for cancer in human diseases. Relevantly, a number of RPs have been shown to bind to MDM2 and inhibit MDM2 E3 liga...
| Glavni autori: | , , , |
|---|---|
| Format: | Članak |
| Jezik: | English |
| Izdano: |
Public Library of Science (PLoS)
2013-01-01
|
| Serija: | PLoS ONE |
| Online pristup: | http://europepmc.org/articles/PMC3713000?pdf=render |