A New Synthetic Curcuminoid Displays Antitumor Activities in Metastasized Melanoma

A New Synthetic Curcuminoid Displays Antitumor Activities in Metastasized Melanoma

Aim: The semisynthetic derivatives MePip-SF5 and isogarcinol, which are aligned with the natural products curcumin and garcinol, were tested for their antitumor effects in a preclinical model of pulmonary melanoma metastasis. Methods and results: MePip-SF5 was almost five times more effective in inh...

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Bibliographic Details
Main Authors: Leonard Kaps, Adrian Klefenz, Henry Traenckner, Paul Schneider, Ion Andronache, Rainer Schobert, Bernhard Biersack, Detlef Schuppan
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
black skin cancer
solid cancer
synthetic derivative of natural product
anticancer drug
curcuma longa
Ayurveda
Online Access:https://www.mdpi.com/2073-4409/12/22/2619

Internet

https://www.mdpi.com/2073-4409/12/22/2619

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