Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition
Nutritional ultrasonography is an emerging technique for measuring muscle mass and quality. The study aimed to evaluate the relationship between the parameters of body mass and quality of ultrasonography with other parameters of morphofunctional assessment in patients with disease-related malnutriti...
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MDPI AG
2023-09-01
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author | Juan José López-Gómez David García-Beneitez Rebeca Jiménez-Sahagún Olatz Izaola-Jauregui David Primo-Martín Beatriz Ramos-Bachiller Emilia Gómez-Hoyos Esther Delgado-García Paloma Pérez-López Daniel A. De Luis-Román |
author_facet | Juan José López-Gómez David García-Beneitez Rebeca Jiménez-Sahagún Olatz Izaola-Jauregui David Primo-Martín Beatriz Ramos-Bachiller Emilia Gómez-Hoyos Esther Delgado-García Paloma Pérez-López Daniel A. De Luis-Román |
author_sort | Juan José López-Gómez |
collection | DOAJ |
description | Nutritional ultrasonography is an emerging technique for measuring muscle mass and quality. The study aimed to evaluate the relationship between the parameters of body mass and quality of ultrasonography with other parameters of morphofunctional assessment in patients with disease-related malnutrition (DRM). Methods: A cross-sectional study was developed on 144 patients diagnosed with DRM according to the Global Leadership Initiative on Malnutrition (GLIM) criteria. Morphofunctional evaluation was assessed with anthropometric variables, handgrip strength and bioelectrical impedanciometry (BIA). Nutritional ultrasonography of quadriceps rectus femoris (QRF) was made (muscle mass (Muscle Area of Rectus Femoris index (MARFI)), Y axis and muscle quality (X-Y index and echogenicity). Results: The mean age of patients was 61.4 (17.34) years. The prevalence of sarcopenia in the sample was 33.3%. Patients with sarcopenia (S) had lower values of MARFI [(S: 1.09 (0.39) cm<sup>2</sup>/m<sup>2</sup>; NoS: 1.27 (0.45); <i>p</i> = 0.02), Y axis (S: 0.88 (0.27); NoS: 1.19 (0.60); <i>p</i> < 0.01) and X-Y index (S: 1.52 (0.61); NoS: 1.30 (0.53); <i>p</i> < 0.01)]. There was a correlation between BIA parameters (phase angle) and muscle mass ultrasonographic variables (MARFI) (r = 0.35; <i>p</i> < 0.01); there was an inverse correlation between muscle quality ultrasonographic variables (echogenicity) and handgrip strength (r = −0.36; <i>p</i> < 0.01). In the multivariate analysis adjusted by age, the highest quartile of the X-Y index had more risk of death OR: 4.54 CI95% (1.11–18.47). Conclusions: In patients with DRM and sarcopenia, standardized muscle mass and muscle quality parameters determined by ultrasonography of QRF are worse than in patients without sarcopenia. Muscle quality parameters had an inverse correlation with electric parameters from BIA and muscle strength. The highest quartile of the X-Y index determined by ultrasonography was associated with increased mortality risk. |
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spelling | doaj.art-4f58f1d039894b789a9d0cb6f9e34ac02023-11-19T12:17:45ZengMDPI AGNutrients2072-66432023-09-011518392310.3390/nu15183923Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related MalnutritionJuan José López-Gómez0David García-Beneitez1Rebeca Jiménez-Sahagún2Olatz Izaola-Jauregui3David Primo-Martín4Beatriz Ramos-Bachiller5Emilia Gómez-Hoyos6Esther Delgado-García7Paloma Pérez-López8Daniel A. De Luis-Román9Servicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainFacultad de Medicina, Universidad de Medicina, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainNutritional ultrasonography is an emerging technique for measuring muscle mass and quality. The study aimed to evaluate the relationship between the parameters of body mass and quality of ultrasonography with other parameters of morphofunctional assessment in patients with disease-related malnutrition (DRM). Methods: A cross-sectional study was developed on 144 patients diagnosed with DRM according to the Global Leadership Initiative on Malnutrition (GLIM) criteria. Morphofunctional evaluation was assessed with anthropometric variables, handgrip strength and bioelectrical impedanciometry (BIA). Nutritional ultrasonography of quadriceps rectus femoris (QRF) was made (muscle mass (Muscle Area of Rectus Femoris index (MARFI)), Y axis and muscle quality (X-Y index and echogenicity). Results: The mean age of patients was 61.4 (17.34) years. The prevalence of sarcopenia in the sample was 33.3%. Patients with sarcopenia (S) had lower values of MARFI [(S: 1.09 (0.39) cm<sup>2</sup>/m<sup>2</sup>; NoS: 1.27 (0.45); <i>p</i> = 0.02), Y axis (S: 0.88 (0.27); NoS: 1.19 (0.60); <i>p</i> < 0.01) and X-Y index (S: 1.52 (0.61); NoS: 1.30 (0.53); <i>p</i> < 0.01)]. There was a correlation between BIA parameters (phase angle) and muscle mass ultrasonographic variables (MARFI) (r = 0.35; <i>p</i> < 0.01); there was an inverse correlation between muscle quality ultrasonographic variables (echogenicity) and handgrip strength (r = −0.36; <i>p</i> < 0.01). In the multivariate analysis adjusted by age, the highest quartile of the X-Y index had more risk of death OR: 4.54 CI95% (1.11–18.47). Conclusions: In patients with DRM and sarcopenia, standardized muscle mass and muscle quality parameters determined by ultrasonography of QRF are worse than in patients without sarcopenia. Muscle quality parameters had an inverse correlation with electric parameters from BIA and muscle strength. The highest quartile of the X-Y index determined by ultrasonography was associated with increased mortality risk.https://www.mdpi.com/2072-6643/15/18/3923nutritional ultrasonographydisease-related malnutritionmorphofunctional assessmentechogenicity |
spellingShingle | Juan José López-Gómez David García-Beneitez Rebeca Jiménez-Sahagún Olatz Izaola-Jauregui David Primo-Martín Beatriz Ramos-Bachiller Emilia Gómez-Hoyos Esther Delgado-García Paloma Pérez-López Daniel A. De Luis-Román Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition Nutrients nutritional ultrasonography disease-related malnutrition morphofunctional assessment echogenicity |
title | Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition |
title_full | Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition |
title_fullStr | Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition |
title_full_unstemmed | Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition |
title_short | Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition |
title_sort | nutritional ultrasonography a method to evaluate muscle mass and quality in morphofunctional assessment of disease related malnutrition |
topic | nutritional ultrasonography disease-related malnutrition morphofunctional assessment echogenicity |
url | https://www.mdpi.com/2072-6643/15/18/3923 |
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