Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition

Nutritional ultrasonography is an emerging technique for measuring muscle mass and quality. The study aimed to evaluate the relationship between the parameters of body mass and quality of ultrasonography with other parameters of morphofunctional assessment in patients with disease-related malnutriti...

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Main Authors: Juan José López-Gómez, David García-Beneitez, Rebeca Jiménez-Sahagún, Olatz Izaola-Jauregui, David Primo-Martín, Beatriz Ramos-Bachiller, Emilia Gómez-Hoyos, Esther Delgado-García, Paloma Pérez-López, Daniel A. De Luis-Román
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/15/18/3923
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author Juan José López-Gómez
David García-Beneitez
Rebeca Jiménez-Sahagún
Olatz Izaola-Jauregui
David Primo-Martín
Beatriz Ramos-Bachiller
Emilia Gómez-Hoyos
Esther Delgado-García
Paloma Pérez-López
Daniel A. De Luis-Román
author_facet Juan José López-Gómez
David García-Beneitez
Rebeca Jiménez-Sahagún
Olatz Izaola-Jauregui
David Primo-Martín
Beatriz Ramos-Bachiller
Emilia Gómez-Hoyos
Esther Delgado-García
Paloma Pérez-López
Daniel A. De Luis-Román
author_sort Juan José López-Gómez
collection DOAJ
description Nutritional ultrasonography is an emerging technique for measuring muscle mass and quality. The study aimed to evaluate the relationship between the parameters of body mass and quality of ultrasonography with other parameters of morphofunctional assessment in patients with disease-related malnutrition (DRM). Methods: A cross-sectional study was developed on 144 patients diagnosed with DRM according to the Global Leadership Initiative on Malnutrition (GLIM) criteria. Morphofunctional evaluation was assessed with anthropometric variables, handgrip strength and bioelectrical impedanciometry (BIA). Nutritional ultrasonography of quadriceps rectus femoris (QRF) was made (muscle mass (Muscle Area of Rectus Femoris index (MARFI)), Y axis and muscle quality (X-Y index and echogenicity). Results: The mean age of patients was 61.4 (17.34) years. The prevalence of sarcopenia in the sample was 33.3%. Patients with sarcopenia (S) had lower values of MARFI [(S: 1.09 (0.39) cm<sup>2</sup>/m<sup>2</sup>; NoS: 1.27 (0.45); <i>p</i> = 0.02), Y axis (S: 0.88 (0.27); NoS: 1.19 (0.60); <i>p</i> < 0.01) and X-Y index (S: 1.52 (0.61); NoS: 1.30 (0.53); <i>p</i> < 0.01)]. There was a correlation between BIA parameters (phase angle) and muscle mass ultrasonographic variables (MARFI) (r = 0.35; <i>p</i> < 0.01); there was an inverse correlation between muscle quality ultrasonographic variables (echogenicity) and handgrip strength (r = −0.36; <i>p</i> < 0.01). In the multivariate analysis adjusted by age, the highest quartile of the X-Y index had more risk of death OR: 4.54 CI95% (1.11–18.47). Conclusions: In patients with DRM and sarcopenia, standardized muscle mass and muscle quality parameters determined by ultrasonography of QRF are worse than in patients without sarcopenia. Muscle quality parameters had an inverse correlation with electric parameters from BIA and muscle strength. The highest quartile of the X-Y index determined by ultrasonography was associated with increased mortality risk.
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spelling doaj.art-4f58f1d039894b789a9d0cb6f9e34ac02023-11-19T12:17:45ZengMDPI AGNutrients2072-66432023-09-011518392310.3390/nu15183923Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related MalnutritionJuan José López-Gómez0David García-Beneitez1Rebeca Jiménez-Sahagún2Olatz Izaola-Jauregui3David Primo-Martín4Beatriz Ramos-Bachiller5Emilia Gómez-Hoyos6Esther Delgado-García7Paloma Pérez-López8Daniel A. De Luis-Román9Servicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainFacultad de Medicina, Universidad de Medicina, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainNutritional ultrasonography is an emerging technique for measuring muscle mass and quality. The study aimed to evaluate the relationship between the parameters of body mass and quality of ultrasonography with other parameters of morphofunctional assessment in patients with disease-related malnutrition (DRM). Methods: A cross-sectional study was developed on 144 patients diagnosed with DRM according to the Global Leadership Initiative on Malnutrition (GLIM) criteria. Morphofunctional evaluation was assessed with anthropometric variables, handgrip strength and bioelectrical impedanciometry (BIA). Nutritional ultrasonography of quadriceps rectus femoris (QRF) was made (muscle mass (Muscle Area of Rectus Femoris index (MARFI)), Y axis and muscle quality (X-Y index and echogenicity). Results: The mean age of patients was 61.4 (17.34) years. The prevalence of sarcopenia in the sample was 33.3%. Patients with sarcopenia (S) had lower values of MARFI [(S: 1.09 (0.39) cm<sup>2</sup>/m<sup>2</sup>; NoS: 1.27 (0.45); <i>p</i> = 0.02), Y axis (S: 0.88 (0.27); NoS: 1.19 (0.60); <i>p</i> < 0.01) and X-Y index (S: 1.52 (0.61); NoS: 1.30 (0.53); <i>p</i> < 0.01)]. There was a correlation between BIA parameters (phase angle) and muscle mass ultrasonographic variables (MARFI) (r = 0.35; <i>p</i> < 0.01); there was an inverse correlation between muscle quality ultrasonographic variables (echogenicity) and handgrip strength (r = −0.36; <i>p</i> < 0.01). In the multivariate analysis adjusted by age, the highest quartile of the X-Y index had more risk of death OR: 4.54 CI95% (1.11–18.47). Conclusions: In patients with DRM and sarcopenia, standardized muscle mass and muscle quality parameters determined by ultrasonography of QRF are worse than in patients without sarcopenia. Muscle quality parameters had an inverse correlation with electric parameters from BIA and muscle strength. The highest quartile of the X-Y index determined by ultrasonography was associated with increased mortality risk.https://www.mdpi.com/2072-6643/15/18/3923nutritional ultrasonographydisease-related malnutritionmorphofunctional assessmentechogenicity
spellingShingle Juan José López-Gómez
David García-Beneitez
Rebeca Jiménez-Sahagún
Olatz Izaola-Jauregui
David Primo-Martín
Beatriz Ramos-Bachiller
Emilia Gómez-Hoyos
Esther Delgado-García
Paloma Pérez-López
Daniel A. De Luis-Román
Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition
Nutrients
nutritional ultrasonography
disease-related malnutrition
morphofunctional assessment
echogenicity
title Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition
title_full Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition
title_fullStr Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition
title_full_unstemmed Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition
title_short Nutritional Ultrasonography, a Method to Evaluate Muscle Mass and Quality in Morphofunctional Assessment of Disease Related Malnutrition
title_sort nutritional ultrasonography a method to evaluate muscle mass and quality in morphofunctional assessment of disease related malnutrition
topic nutritional ultrasonography
disease-related malnutrition
morphofunctional assessment
echogenicity
url https://www.mdpi.com/2072-6643/15/18/3923
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