Plant-Derived Molecule 4-Methylumbelliferone Suppresses FcεRI-Mediated Mast Cell Activation and Allergic Inflammation

Plant-Derived Molecule 4-Methylumbelliferone Suppresses FcεRI-Mediated Mast Cell Activation and Allergic Inflammation

Mast cells (MCs) are an important treatment target for high-affinity IgE Fc receptor (FcεRI)-mediated allergic diseases. The plant-derived molecule 4-methylumbelliferone (4-MU) has beneficial effects in animal models of inflammation and autoimmunity diseases. The aim of this study was to examine 4-M...

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Bibliographic Details
Main Authors: Hui-Na Wang, Qiu-An Xiang, Hao-Hui Lin, Jie-Ning Chen, Wen-Jie Guo, Wan-Meng Guo, Xiang-Ning Yue, Zhen-Fu Zhao, Kunmei Ji, Jia-Jie Chen
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
4-methylumbelliferone
mast cell
FcεRI signaling
SYK
Online Access:https://www.mdpi.com/1420-3049/27/5/1577

Internet

https://www.mdpi.com/1420-3049/27/5/1577

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