The combination of Astragalus membranaceus and ligustrazine mitigates cerebral ischemia‐reperfusion injury via regulating NR2B‐ERK/CREB signaling

The combination of Astragalus membranaceus and ligustrazine mitigates cerebral ischemia‐reperfusion injury via regulating NR2B‐ERK/CREB signaling

Abstract Background and purpose Cerebral ischemia‐reperfusion (I/R) injury is a major factor underlying the high mortality and morbidity rates in stroke patients. Our previous study found that the combination of Astragalus membranaceus extract and ligustrazine (Ast+Lig) treatment could protect brain...

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Bibliographic Details
Main Authors: Xialing Tang, Shanshan Xie, Huajun Wang, Yingbin Li, Zhiyu Lai, Shuangxi Sun, Ruanhuan Pan, Yan Huang, Jun Cai
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Brain and Behavior
Subjects:
Astragalus membranaceus
cerebral ischemia‐reperfusion injury
ligustrazine
N‐methyl‐D‐aspartate receptors
stroke
Online Access:https://doi.org/10.1002/brb3.2867

Internet

https://doi.org/10.1002/brb3.2867

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