Enhanced CD8 + T-cell response in mice immunized with NS1-truncated influenza virus

Influenza viruses with truncated NS1 protein stimulate a more intensive innate immune response compared to their wild type counterparts. Here, we investigate how the shortening of the NS1 protein influence the immunogenicity of the conserved T-cellular epitopes of influenza virus. Using flow cytomet...

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Bibliographic Details
Main Authors: Kirill A. Vasilyev, Anna-Polina S. Shurygina, Marina A. Stukova, Andrej Y. Egorov
Format: Article
Language:English
Published: Doctrine 2020-02-01
Series:Microbiology Independent Research Journal
Online Access:https://www.scienceopen.com/hosted-document?doi=10.18527/2500-2236-2020-7-1-24-33