CTLA4+CD4+CXCR5−FOXP3+ T cells associate with unfavorable outcome in patients with chronic HBV infection

Abstract Background A major barrier to achieving a favorable outcome of chronic HBV infection is a dysregulated HBV-specific immune response resulting from immunosuppressive features of FOXP3+ T cells. A better definition of FOXP3+ T cells is essential for improving the prognosis of HBV infection. W...

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Bibliographic Details
Main Authors: Chunhua Wen, Zheyu Dong, Yiyue Wang, Guofu Ye, Yanchen Ma, Xuan Yi, Yang Zhou, Xiaoyi Li, Xinchun Zheng, Jinlin Hou, Yongyin Li, Libo Tang
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Immunology
Subjects:
Online Access:https://doi.org/10.1186/s12865-022-00537-w