Prognostic impact of ZAP-70 expression in chronic lymphocytic leukemia: mean fluorescence intensity T/B ratio versus percentage of positive cells

<p>Abstract</p> <p>Background</p> <p>ZAP-70 is an independent negative prognostic marker in chronic lymphocytic leukemia (CLL). Usually, its expression is investigated by flow cytometric protocols in which the percentage of ZAP-70 positive CLL cells is determined in res...

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Main Authors: Degan Massimo, Benedetti Dania, Fangazio Marco, Dal Bo Michele, Bomben Riccardo, Bulian Pietro, Zucchetto Antonella, Luciano Fabrizio, Irno Consalvo Maria, Rossi Davide, Del Principe Maria Ilaria, Rossi Francesca M, Gaidano Gianluca, Del Poeta Giovanni, Gattei Valter
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/8/1/23