Bioinformatics-Based Characterization of ATP-Binding Cassette Subfamily B Member 1 (<i>ABCB1</i>) Gene Expression in Non-Small-Cell Lung Cancer (NSCLC)

Bioinformatics-Based Characterization of ATP-Binding Cassette Subfamily B Member 1 (<i>ABCB1</i>) Gene Expression in Non-Small-Cell Lung Cancer (NSCLC)

P-glycoprotein (P-gp) has been implicated in lung cancer development, disease progression, and patient survival. Changes in the <i>ABCB1</i> expression level may correlate with tumorigenesis and the formation of multidrug resistance (MDR). In addition, epigenetic modifications such as DN...

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Bibliographic Details
Main Authors: Agnieszka Maria Jeleń, Bartłomiej Strehl, Dagmara Szmajda-Krygier, Milena Pązik, Ewa Balcerczak
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Applied Sciences
Subjects:
<i>ABCB1</i>
cancer progression
prognostic biomarker
lung cancer
DNA methylation
Online Access:https://www.mdpi.com/2076-3417/13/11/6576

Internet

https://www.mdpi.com/2076-3417/13/11/6576

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