Model-Informed Drug Discovery and Development Strategy for the Rapid Development of Anti-Tuberculosis Drug Combinations

Model-Informed Drug Discovery and Development Strategy for the Rapid Development of Anti-Tuberculosis Drug Combinations

The increasing emergence of drug-resistant tuberculosis requires new effective and safe drug regimens. However, drug discovery and development are challenging, lengthy and costly. The framework of model-informed drug discovery and development (MID3) is proposed to be applied throughout the preclinic...

Full description

Bibliographic Details
Main Authors: Rob C. van Wijk, Rami Ayoun Alsoud, Hans Lennernäs, Ulrika S. H. Simonsson
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Applied Sciences
Subjects:
tuberculosis
MID3
pharmacokinetics
pharmacodynamics
drug-drug interactions
<i>in vitro</i>
Online Access:https://www.mdpi.com/2076-3417/10/7/2376

Internet

https://www.mdpi.com/2076-3417/10/7/2376

Similar Items