Data Size and Quality Matter: Generating Physically-Realistic Distance Maps of Protein Tertiary Structures

Data Size and Quality Matter: Generating Physically-Realistic Distance Maps of Protein Tertiary Structures

With the debut of AlphaFold2, we now can get a highly-accurate view of a reasonable equilibrium tertiary structure of a protein molecule. Yet, a single-structure view is insufficient and does not account for the high structural plasticity of protein molecules. Obtaining a multi-structure view of a p...

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Bibliographic Details
Main Authors: Fardina Fathmiul Alam, Amarda Shehu
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biomolecules
Subjects:
protein molecule
tertiary structure
multi-structure view
generative model
variational autoencoder
spatial pyramidal pooling
Online Access:https://www.mdpi.com/2218-273X/12/7/908

Internet

https://www.mdpi.com/2218-273X/12/7/908

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