Synthetic dimethoxyxanthones bind similarly to human serum albumin compared with highly oxygenated xanthones

Synthetic dimethoxyxanthones bind similarly to human serum albumin compared with highly oxygenated xanthones

Spectroscopic studies were carried out for the interaction of the bioactive compounds 2,3-dimethoxyxanthone (1) and 3,4-dimethoxyxanthone (2) with human serum albumin (HSA). The UV absorption, steady-state, and time-resolved fluorescence spectroscopy studies showed that 1 and 2 interact with HSA thr...

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Bibliographic Details
Main Authors: Otávio Augusto Chaves, Cosme H.C. dos Santos Oliveira, Romulo Correia Ferreira, Dari Cesarin-Sobrinho, Antonio Eduardo da Hora Machado, José Carlos Netto-Ferreira
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Chemical Physics Impact
Subjects:
Xanthones
Human serum albumin
Spectroscopy
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S2667022423002505

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http://www.sciencedirect.com/science/article/pii/S2667022423002505

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