Experimental Traumatic Brain Injury Induces Chronic Glutamatergic Dysfunction in Amygdala Circuitry Known to Regulate Anxiety-Like Behavior

Experimental Traumatic Brain Injury Induces Chronic Glutamatergic Dysfunction in Amygdala Circuitry Known to Regulate Anxiety-Like Behavior

Up to 50% of traumatic brain injury (TBI) survivors demonstrate persisting and late-onset anxiety disorders indicative of limbic system dysregulation, yet the pathophysiology underlying the symptoms is unclear. We hypothesize that the development of TBI-induced anxiety-like behavior in an experiment...

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Bibliographic Details
Main Authors: Joshua A. Beitchman, Daniel R. Griffiths, Yerin Hur, Sarah B. Ogle, Caitlin E. Bromberg, Helena W. Morrison, Jonathan Lifshitz, P. David Adelson, Theresa Currier Thomas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Neuroscience
Subjects:
diffuse traumatic brain injury
amperometry
glutamate neurotransmission
amygdala
chronic
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01434/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01434/full

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