The role of DNA demethylation in liver to pancreas transdifferentiation

The role of DNA demethylation in liver to pancreas transdifferentiation

Abstract Background Insulin producing cells generated by liver cell transdifferentiation, could serve as an attractive source for regenerative medicine. The present study assesses the relationship between DNA methylation pTFs induced liver to pancreas transdifferentiation. Results The transdifferent...

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Bibliographic Details
Main Authors: Adi Har-Zahav, Daniela Lixandru, David Cheishvili, Ioan Valentin Matei, Ioana Raluca Florea, Veronica Madalina Aspritoiu, Inna Blus-Kadosh, Irit Meivar-Levy, Andreea Madalina Serban, Irinel Popescu, Moshe Szyf, Sarah Ferber, Simona Olimpia Dima
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Stem Cell Research & Therapy
Subjects:
Transdifferentiation
Liver
Pancreas
Pancreatic transcription factors
Epigenetic modifications
DNA methylation
Online Access:https://doi.org/10.1186/s13287-022-03159-6

Internet

https://doi.org/10.1186/s13287-022-03159-6

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