Ovarian cancer relies on the PDGFRβ–fibronectin axis for tumorsphere formation and metastatic spread

Ovarian cancer relies on the PDGFRβ–fibronectin axis for tumorsphere formation and metastatic spread

High‐grade serous ovarian cancer (HGSOC) is the deadliest gynecological malignancy. The most common form of metastatic spread of HGSOC is transcoelomic dissemination. In this process, detached cells from the primary tumor aggregate as tumorspheres and promote the accumulation of peritoneal ascites....

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Bibliographic Details
Main Authors: Núria Gendrau‐Sanclemente, Agnès Figueras, Kristina Gracova, Álvaro Lahiguera, Elisenda Alsina‐Sanchís, Juan A. Marín‐Jiménez, August Vidal, Xavier Matias‐Guiu, Sergi Fernandez‐Gonzalez, Marc Barahona, Lola Martí, Jordi Ponce, Francesc Viñals
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Molecular Oncology
Subjects:
fibronectin
HGSOC
metastasis
ovarian cancer
PDGFRβ
tumorspheres
Online Access:https://doi.org/10.1002/1878-0261.13556

Internet

https://doi.org/10.1002/1878-0261.13556

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