Population pharmacokinetic models of anti-PD-1 mAbs in patients with multiple tumor types: A systematic review

Population pharmacokinetic models of anti-PD-1 mAbs in patients with multiple tumor types: A systematic review

Aims and backgroundA number of population pharmacokinetic (PPK) models of anti-programmed cell death-1 (PD-1) monoclonal antibodies (mAbs) in multiple tumor types have been published to characterize the influencing factors of their pharmacokinetics. This review described PPK models of anti-PD-1 mAbs...

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Bibliographic Details
Main Authors: Jingyuan Shang, Lin Huang, Jing Huang, Xiaolei Ren, Yi Liu, Yufei Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
anti-PD-1 mAbs
immune checkpoint inhibitors
population pharmacokinetics
PPK model
systematic review
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.871372/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.871372/full

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