Theoretical Study on Zearalenol Compounds Binding with Wild Type Zearalenone Hydrolase and V153H Mutant

Theoretical Study on Zearalenol Compounds Binding with Wild Type Zearalenone Hydrolase and V153H Mutant

Zearalenone hydrolase (ZHD) is the only reported α/β-hydrolase that can detoxify zearalenone (ZEN). ZHD has demonstrated its potential as a treatment for ZEN contamination that will not result in damage to cereal crops. Recent researches have shown that the V153H mutant ZHD increa...

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Bibliographic Details
Main Authors: Ye Liu, Youzhong Wan, Jingxuan Zhu, Zhengfei Yu, Xiaopian Tian, Jiarui Han, Zuoming Zhang, Weiwei Han
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
zearalenone hydrolase
molecular dynamics simulation
protein network analysis
alanine scanning
conformational change
Online Access:http://www.mdpi.com/1422-0067/19/9/2808

Internet

http://www.mdpi.com/1422-0067/19/9/2808

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