Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

Abstract Background Sepsis is a multi-system syndrome that remains the leading cause of mortality and critical illness worldwide, with hemodynamic support being one of the cornerstones of the acute management of sepsis. We used an ovine model of endotoxemic shock to determine if 0.9% saline resuscit...

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Bibliographic Details
Main Authors: Margaret R. Passmore, Liam Byrne, Nchafatso G. Obonyo, Louise E. See Hoe, Ai-Ching Boon, Sara D. Diab, Kimble R. Dunster, Kavita Bisht, John-Paul Tung, Mohd H. Fauzi, Monica Narula, Sanne E. Pedersen, Arlanna Esguerra-Lallen, Gabriela Simonova, Annette Sultana, Chris M. Anstey, Kiran Shekar, Kathryn Maitland, Jacky Y. Suen, John F. Fraser
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Respiratory Research
Subjects:
Endotoxemic shock
Inflammation
Lung injury
Matrix metalloproteinases
Online Access:http://link.springer.com/article/10.1186/s12931-018-0935-4

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http://link.springer.com/article/10.1186/s12931-018-0935-4

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