Rodents on a high-fat diet born to mothers with gestational diabetes exhibit sex-specific lipidomic changes in reproductive organs

Rodents on a high-fat diet born to mothers with gestational diabetes exhibit sex-specific lipidomic changes in reproductive organs

Maternal gestatonal diabetes mellitus (GDM) and offspring high-fat diet (HFD) have been shown to have sex-specific detrimental effects on the health of the offspring. Maternal GDM combined with an offspring HFD alters the lipidomic profiles of offspring reproductive organs with sex hormones and incr...

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Bibliographic Details
Main Authors: Wang Andi, Luo Baiyu, Chen Zhu, Xia Yinyin, Chen Chang, Qi Hongbo, Baker Philip N., Saffery Richard, Han Ting-Li, Zhang Hua
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-05-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
maternal GDM
mice offspring
metabolomics
hormone
insulin signaling
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022052

Internet

https://www.sciengine.com/doi/10.3724/abbs.2022052

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