Transcriptional Regulator DasR Represses Daptomycin Production through Both Direct and Cascade Mechanisms in <i>Streptomyces roseosporus</i>

Daptomycin, produced by <i>Streptomyces roseosporus</i>, is a clinically important cyclic lipopeptide antibiotic used for the treatment of human infections caused by drug-resistant Gram-positive pathogens. In contrast to most <i>Streptomyces</i> antibiotic biosynthetic gene c...

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Bibliographic Details
Main Authors: Qiong Chen, Jianya Zhu, Xingwang Li, Ying Wen
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/11/8/1065