Transcriptional Regulator DasR Represses Daptomycin Production through Both Direct and Cascade Mechanisms in <i>Streptomyces roseosporus</i>
Daptomycin, produced by <i>Streptomyces roseosporus</i>, is a clinically important cyclic lipopeptide antibiotic used for the treatment of human infections caused by drug-resistant Gram-positive pathogens. In contrast to most <i>Streptomyces</i> antibiotic biosynthetic gene c...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-08-01
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Series: | Antibiotics |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-6382/11/8/1065 |