Lipid profiling following intake of the omega 3 fatty acid DHA identifies the peroxidized metabolites F4-neuroprostanes as the best predictors of atherosclerosis prevention.

The anti-atherogenic effects of omega 3 fatty acids, namely eicosapentaenoic (EPA) and docosahexaenoic acids (DHA) are well recognized but the impact of dietary intake on bioactive lipid mediator profiles remains unclear. Such a profiling effort may offer novel targets for future studies into the me...

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Main Authors: Cécile Gladine, John W Newman, Thierry Durand, Theresa L Pedersen, Jean-Marie Galano, Céline Demougeot, Olivier Berdeaux, Estelle Pujos-Guillot, Andrzej Mazur, Blandine Comte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3928438?pdf=render