Development of a novel thymidylate synthase (TS) inhibitor capable of up-regulating P53 expression and inhibiting angiogenesis in NSCLC

Introduction: The development of a new type of Thymidylate synthase (TS) inhibitor that could inhibit cancer cells' proliferation and anti-angiogenesis is of great significance for cancer's clinical treatment. Objectives: Our research hopes to develop a TS inhibitor that is more effective...

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Bibliographic Details
Main Authors: Xin-yang Li, De-pu Wang, Guo-qing Lu, Kai-li Liu, Ting-jian Zhang, Shuai Li, Kamara Mohamed O, Wen-han Xue, Xin-hua Qian, Fan-hao Meng
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Journal of Advanced Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123220301673