Aptamer-functionalized hydrogels promote bone healing by selectively recruiting endogenous bone marrow mesenchymal stem cells

Aptamer-functionalized hydrogels promote bone healing by selectively recruiting endogenous bone marrow mesenchymal stem cells

Bone regeneration heavily relies on bone marrow mesenchymal stem cells (BMSCs). However, recruiting endogenous BMSCs for in situ bone regeneration remains challenging. In this study, we developed a novel BMSC-aptamer (BMSC-apt) functionalized hydrogel (BMSC-aptgel) and evaluated its functions in rec...

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Bibliographic Details
Main Authors: Jiang-Shan Gong, Guo-Qiang Zhu, Yu Zhang, Bei Chen, Yi-Wei Liu, Hong-Ming Li, Ze-Hui He, Jing-Tao Zou, Yu-Xuan Qian, Sheng Zhu, Xin-Yue Hu, Shan-Shan Rao, Jia Cao, Hui Xie, Zhen-Xing Wang, Wei Du
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Materials Today Bio
Subjects:
Aptamer
Hydrogel
Fracture
Endogenous
Bone marrow mesenchymal stem cells
In situ regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423003149

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http://www.sciencedirect.com/science/article/pii/S2590006423003149

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