Insulin-like Growth Factor-1 Influences Prostate Cancer Cell Growth and Invasion through an Integrin α3, α5, αV, and β1 Dependent Mechanism

Insulin-like Growth Factor-1 Influences Prostate Cancer Cell Growth and Invasion through an Integrin α3, α5, αV, and β1 Dependent Mechanism

Insulin-like growth factor-1 (IGF-1)-related signaling is associated with prostate cancer progression. Links were explored between IGF-1 and expression of integrin adhesion receptors to evaluate relevance for growth and migration. Androgen-resistant PC3 and DU145 and androgen-sensitive LNCaP and VCa...

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Bibliographic Details
Main Authors: Carolin Siech, Jochen Rutz, Sebastian Maxeiner, Timothy Grein, Marlon Sonnenburg, Igor Tsaur, Felix K.-H. Chun, Roman A. Blaheta
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
prostate cancer
IGF-1
Akt-mTOR pathway
integrins
growth
invasion
Online Access:https://www.mdpi.com/2072-6694/14/2/363

Internet

https://www.mdpi.com/2072-6694/14/2/363

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