A therapeutic antibody against west nile virus neutralizes infection by blocking fusion within endosomes.
Defining the precise cellular mechanisms of neutralization by potently inhibitory antibodies is important for understanding how the immune system successfully limits viral infections. We recently described a potently inhibitory monoclonal antibody (MAb E16) against the envelope (E) protein of West N...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-05-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2679195?pdf=render |