Risk factors for oral methotrexate failure in patients with inflammatory polyarthritis: results from a UK prospective cohort study

Risk factors for oral methotrexate failure in patients with inflammatory polyarthritis: results from a UK prospective cohort study

Abstract Background Oral methotrexate (MTX) is the first-line therapy for patients with rheumatoid arthritis (RA). However, approximately one quarter of patients discontinue MTX within 12 months. MTX failure, defined as MTX cessation or the addition of another anti-rheumatic drug, is usually due adv...

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Bibliographic Details
Main Authors: James Bluett, Jamie C. Sergeant, Alex J. MacGregor, Jacqueline R. Chipping, Tarnya Marshall, Deborah P. M. Symmons, Suzanne M. M. Verstappen
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Arthritis Research & Therapy
Subjects:
Methotrexate
Medication persistence
Competing risk analysis
Arthritis
Treatment failure
Online Access:http://link.springer.com/article/10.1186/s13075-018-1544-9

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http://link.springer.com/article/10.1186/s13075-018-1544-9

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