Identification of a Novel Curcumin Derivative Influencing Notch Pathway and DNA Damage as a Potential Therapeutic Agent in T-ALL

Identification of a Novel Curcumin Derivative Influencing Notch Pathway and DNA Damage as a Potential Therapeutic Agent in T-ALL

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy considered curable by modern clinical management. Nevertheless, the prognosis for T-ALL high-risk cases or patients with relapsed and refractory disease is still dismal. Therefore, there is a keen interest in devel...

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Bibliographic Details
Main Authors: Nadezda Zhdanovskaya, Sara Lazzari, Diego Caprioglio, Mariarosaria Firrincieli, Chiara Maioli, Eleonora Pace, Daniela Imperio, Claudio Talora, Diana Bellavia, Saula Checquolo, Mattia Mori, Isabella Screpanti, Alberto Minassi, Rocco Palermo
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
curcumin
curcuminoids
T-ALL
leukemia
Notch signaling
cancer
Online Access:https://www.mdpi.com/2072-6694/14/23/5772

Internet

https://www.mdpi.com/2072-6694/14/23/5772

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