Induction of CD4<sup>+</sup>CD25<sup>+</sup> Regulatory T Cells from In Vitro Grown Human Mononuclear Cells by Sparteine Sulfate and Harpagoside

Regulatory T cells (Tregs) are key players in the regulation of inflammatory responses. In this study, two natural molecules, namely, sparteine sulfate (SS) and harpagoside (Harp), were investigated for their ability to induce Tregs in human peripheral blood mononuclear cells (PBMCs). PBMCs were iso...

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Bibliographic Details
Main Authors: Nour Z. Atwany, Seyedeh-Khadijeh Hashemi, Manju Nidagodu Jayakumar, Mitzi Nagarkatti, Prakash Nagarkatti, Mona Rushdi Hassuneh
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/9/8/211