The Brain Endothelial Cell Glycocalyx Plays a Crucial Role in the Development of Enlarged Perivascular Spaces in Obesity, Metabolic Syndrome, and Type 2 Diabetes Mellitus

The Brain Endothelial Cell Glycocalyx Plays a Crucial Role in the Development of Enlarged Perivascular Spaces in Obesity, Metabolic Syndrome, and Type 2 Diabetes Mellitus

The brain endothelial cell (BEC) glycocalyx (ecGCx) is a BEC surface coating consisting of a complex interwoven polysaccharide (sweet husk) mesh-like network of membrane-bound proteoglycans, glycoproteins, and glycosaminoglycans (GAGs) covering the apical luminal layer of the brain endothelial cells...

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Bibliographic Details
Main Author: Melvin R. Hayden
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Life
Subjects:
blood–brain barrier
blood–cerebrospinal fluid barrier
blood–arachnoid barrier
endothelial glycocalyx
enlarged perivascular spaces
metabolic syndrome
Online Access:https://www.mdpi.com/2075-1729/13/10/1955

Internet

https://www.mdpi.com/2075-1729/13/10/1955

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