Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia

<p>Abstract</p> <p>Background</p> <p>A considerable proportion of all newly generated cells in the hippocampus will die before becoming fully differentiated, both under normal and pathological circumstances. The caspase-independent apoptosis-inducing factor (AIF) has no...

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Bibliographic Details
Main Authors: Sun Yanyan, Zhang Yu, Wang Xiaoyang, Blomgren Klas, Zhu Changlian
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:http://www.molecularneurodegeneration.com/content/7/1/17