Mechanical network in titin immunoglobulin from force distribution analysis.

The role of mechanical force in cellular processes is increasingly revealed by single molecule experiments and simulations of force-induced transitions in proteins. How the applied force propagates within proteins determines their mechanical behavior yet remains largely unknown. We present a new met...

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Bibliographic Details
Main Authors: Wolfram Stacklies, M Cristina Vega, Matthias Wilmanns, Frauke Gräter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19282960/pdf/?tool=EBI