Stress Hormones Epinephrine and Corticosterone Selectively Reactivate HSV-1 and HSV-2 in Sympathetic and Sensory Neurons

Herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) establish latency in sensory and autonomic neurons, from which they can reactivate to cause recurrent disease throughout the life of the host. Stress is strongly associated with HSV recurrences in humans and animal models. However, the mechanisms thro...

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Bibliographic Details
Main Authors: Poorna Goswami, Angela M. Ives, Amber R. N. Abbott, Andrea S. Bertke
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/5/1115