Characterization of Mesothelin Glycosylation in Pancreatic Cancer: Decreased Core Fucosylated Glycoforms in Pancreatic Cancer Patients’ Sera

Characterization of Mesothelin Glycosylation in Pancreatic Cancer: Decreased Core Fucosylated Glycoforms in Pancreatic Cancer Patients’ Sera

Currently, there are no reliable biomarkers for the diagnosis of pancreatic cancer (PaC). Glycoproteomic approaches that analyze the glycan determinants on specific glycoproteins have proven useful to develop more specific cancer biomarkers than the corresponding protein levels. In PaC, mesothelin (...

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Bibliographic Details
Main Authors: Adrià Duran, Pedro E. Guerrero, Maria Rosa Ortiz, Dúnia Pérez del Campo, Ernesto Castro, Adelaida Garcia-Velasco, Esther Fort, Rafael de Llorens, Radka Saldova, Esther Llop, Rosa Peracaula
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
pancreatic cancer
biomarkers
mesothelin
<i>N</i>-glycan
lectins
core fucose
Online Access:https://www.mdpi.com/2227-9059/10/8/1942

Internet

https://www.mdpi.com/2227-9059/10/8/1942

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