A Myt1 family transcription factor defines neuronal fate by repressing non-neuronal genes

A Myt1 family transcription factor defines neuronal fate by repressing non-neuronal genes

Cellular differentiation requires both activation of target cell transcriptional programs and repression of non-target cell programs. The Myt1 family of zinc finger transcription factors contributes to fibroblast to neuron reprogramming in vitro. Here, we show that ztf-11 (Zinc-finger Transcription...

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Bibliographic Details
Main Authors: Joo Lee, Caitlin A Taylor, Kristopher M Barnes, Ao Shen, Emerson V Stewart, Allison Chen, Yang K Xiang, Zhirong Bao, Kang Shen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-08-01
Series:eLife
Subjects:
ZTF-11
Myt1
neurogenesis
MuvB complex
transcriptional repression
neuronal differentiation
Online Access:https://elifesciences.org/articles/46703

Internet

https://elifesciences.org/articles/46703

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