Diagnosis of Coxiella burnetii infection: comparison of a whole blood interferon-gamma production assay and a Coxiella ELISPOT.

Diagnosis of Coxiella burnetii infection: comparison of a whole blood interferon-gamma production assay and a Coxiella ELISPOT.

Diagnosis of ongoing or past infection with Coxiella burnetii, the causative agent of Q fever, relies heavily on serology: the measurement of C. burnetii-specific antibodies, reflecting the host's humoral immune response. However, cell-mediated immune responses play an important, probably even...

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Bibliographic Details
Main Authors: Teske Schoffelen, Gijs J M Limonard, Chantal P Bleeker-Rovers, John J M Bouwman, Jos W M van der Meer, Marrigje Nabuurs-Franssen, Tom Sprong, Marcel van Deuren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4118951?pdf=render

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http://europepmc.org/articles/PMC4118951?pdf=render

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