Hematopoietic regulation of transcription factor GATA1 and mutations causing hereditary erythroid and megakaryocytic disorders

Hematopoietic regulation of transcription factor GATA1 and mutations causing hereditary erythroid and megakaryocytic disorders

GATA-binding protein 1 (GATA1), an important hematopoietic transcription factor, specifically regulates the proliferation and differentiation of erythroid and megakaryoid cells at the transcription level, which maintains the normal development and maturation of these two lineages. The functional str...

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Bibliographic Details
Main Authors: Biying DING, Xuefeng WANG
Format: Article
Language:zho
Published: Institute of Blood Transfusion of Chinese Academy of Medical Sciences 2023-01-01
Series:Zhongguo shuxue zazhi
Subjects:
gata-binding protein 1
erythroid lineage
megakaryoid lineage
hematopoietic regulatory disorder
transcriptional regulation
zinc finger
mutation
Online Access:https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2023.01.022&lang=en

Internet

https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2023.01.022&lang=en

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