Alternative splicing of human telomerase reverse transcriptase in gliomas and its modulation mediated by CX-5461

Alternative splicing of human telomerase reverse transcriptase in gliomas and its modulation mediated by CX-5461

Abstract Background Glioma is a heterogeneous, invasive primary brain tumor with a wide range of patient survival and a lack of reliable prognostic biomarkers. Human telomerase reverse transcriptase (hTERT) has been reported in the presence of multiple transcripts in various tumor systems. The biolo...

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Bibliographic Details
Main Authors: Guihong Li, Jing Shen, Junguo Cao, Guangtong Zhou, Ting Lei, Yuxue Sun, Haijun Gao, Yaonan Ding, Weidong Xu, Zhixin Zhan, Yong Chen, Haiyan Huang
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Glioma
Human telomerase reverse transcriptase (hTERT)
Alternative splicing
CX-5461
G-quadruplex
Online Access:http://link.springer.com/article/10.1186/s13046-018-0749-8

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http://link.springer.com/article/10.1186/s13046-018-0749-8

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