Pharmacokinetics of intramuscular alfaxalone and its echocardiographic, cardiopulmonary and sedative effects in healthy dogs.

The pharmacokinetics and the effects of a single intramuscular (IM) dose of alfaxalone on sedation and cardiopulmonary and echocardiographic variables was studied in dogs. Twelve healthy adult Beagles (3 females, 9 males) were used in this prospective controlled cross-over trial. Echocardiography wa...

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Bibliographic Details
Main Authors: Inga-Catalina Cruz-Benedetti, Isabelle Bublot, Thibault Ribas, Isabelle Fourel, Claus Vogl, Claire Dubois, Mathilde Milani, Keila Kazue Ida, Karine Portier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6152991?pdf=render