Isolation of primitive mouse extraembryonic endoderm (pXEN) stem cell lines

Mouse blastocysts contain the committed precursors of the extraembryonic endoderm (ExEn), which express the key transcription factor Oct4, depend on LIF/LIF-like factor-driven Jak/Stat signaling, and initially exhibit lineage plasticity. Previously described rat blastocyst-derived ExEn precursor-lik...

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Bibliographic Details
Main Authors: Yixiang Zhong, Taewoong Choi, Minjae Kim, Kyoung Hwa Jung, Young Gyu Chai, Bert Binas
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506118301260